Thyroid surgery under general anesthesia
Conditions
Interventions
control group:received a bolus dose of intravenous saline and intratracheal 3ml saline
lidcaine local anesthesia group:received a bolus dose of intravenous saline and intratracheal 3ml lidocaine(groupL)
dexmedetomidine group:received a bolus dose of intravenous dexmedetomidine and intratracheal 3ml saline(groupD)
group witha bolus dose of intravenous dexmedetomidine and intratracheal 3ml lidocaine( groupD+L):received a bolus dose of intravenous dexmedetomidine and intratracheal 3ml lidocaine( groupD+L)
Sponsors
First Anesthesiology Departement, Shengjing Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with American Society of Anesthesiologists (ASA) physical status I or II; 2. Aged 17 to 75 years,male or femail; 3. Scheduled to undergo elective unilateral or total thyroidectomy.
Exclusion criteria
Exclusion criteria: 1. The presence of an upper respiratory infection symptom, asthma, difficult airway such as having a history of sleep apnea syndrome, smoking; 2. Poorly controlled hypertension (i.e., systolic blood pressure>160 mmHg or diastolic blood pressure> 90 mmHg), or active coronary artery disease, heart block, bradycardia; 3. Medication with angiotensin converting enzyme (ACE) inhibitors; 4. Mental disorders; 5. History of allergy to the drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence and severity of coughing;Ramsay sedation scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| MAP;HR;visual analogue scale (VAS); | — |
Countries
China
Contacts
Public ContactZhiling Fu
First Anesthesiology Departement, Shengjing Hospital
Outcome results
None listed