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Dexmedetomidine as an analgesic adjuvant to lumber erector spinae ropivacaine for post-orthopedic surgery pain

Dexmedetomidine as an analgesic adjuvant to lumber erector spinae ropivacaine for post-orthopedic surgery pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020940
Enrollment
Unknown
Registered
2019-01-22
Start date
2019-10-01
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip/knee arthroplasty

Interventions

ED1:0.5% ropivacaine 26ml
ED2:0.5% ropivacaine 26ml with DEX 0.5ug/kg
ED3:0.5% ropivacaine 26ml with DEX 1ug/kg

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: ASA I-III, aged 18-75 years old, normal cognitive function, can cooperate with the completion of the experiment.

Exclusion criteria

Exclusion criteria: 1) coagulation dysfunction; 2) puncture point infections; 3) allergic to local anesthetics or opioids; 4) analgesic drug addicts; 5) refusal of ESP blockade. 6) chronic pain, mental or nervous system diseases; 7) severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction.

Design outcomes

Primary

MeasureTime frame
VAS scores in static and dynamic conditions;Duration of the block;The first time of effective pressing of electronic analgesia pump;Effective pressing times of electronic analgesia pump;

Secondary

MeasureTime frame
The dosage of analgesics added at the ward, Medication in operation,Complications after block (hypoxemia, hypotension, sinus bradycardia,somnolence,glossocoma);Complications such as nauseas?vomiting and pneumonia, postoperative hospitalization time;

Countries

China

Contacts

Public ContactLi Yuanhai

The First Affiliated Hospital of Anhui Medical University

liyuanhai-1@163.com+86 13505697561

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026