Inhalation lung injury
Conditions
Interventions
High dose group:2×10^8 cells/10mL
Medium dose group:1×10^8 cells/10mL
Low dose group:0.5×10^8 cells/10mL
Placebo group:0 cells/10mL
Sponsors
Changhai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Comply with the diagnostic criteria for inhaled lung injury, the severity of the disease is moderate and above; (2) Aged between 18 and 60 years old male and female; (3) burn area (TBSA) = 30%, and the depth of burn is deep second degree burn and below; (4) Patients who voluntarily participate in this clinical study and can cooperate with doctors to carry out research and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) ALI/ARDS for non-inhalation lung injury; (2) Patients with physical and mental disabilities; (3) patients with malignant tumors; (4) Concomitant with other serious infectious diseases; (5) HBVHCV or HIV or tuberculosis test positive during patient screening; (6) Pregnant and lactating women; (7) Serious diseases of any major organ (such as heart failure due to lung injury, ventricular fibrillation, renal failure, pulmonary hypertension, cirrhosis); (8) The safety and efficacy evaluation that the investigator believes may affect the study; (9) suspected or confirmed to be allergic to any component of the stem cell preparation of the study; (10) Has participated in clinical research on stem cells.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Simple score of lung contusion; | — |
Countries
China
Contacts
Public ContactFeng Zhu
Shanghai Changhai Hospital
Outcome results
None listed