coronary heart disease
Conditions
Interventions
COG and CG:oral adiminstrated with COS
Sponsors
China-Japan Union Hospital of Jilin University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: The patients had clinical manifestations of typical pain, which was mostly occurred in the early morning. Sudden and severe stern post-sternal or precordial compression pain could be found but the cause was not obvious. Taking a rest or taking nitroglycerin tablets could not alleviate the symptoms. The patients were often upset, sweating, fearful, chest tight or had a sense of death. Typical electrocardiogram showed that ST-segment elevation was arch-back-up with wide and deep Q wave (pathological Q wave) and T wave inversion. The levels of serum myocardial necrosis markers: myoglobin, troponin I (cTnI) or myocardial markers such as cardiac troponin T (cTnT) and creatine kinase isoenzyme CK-MB were significantly elevated.
Exclusion criteria
Exclusion criteria: (1) gastrointestinal diseases, such as gastritis, gastric ulcer, etc., and diarrhea in the past 4 weeks, or a history of gastrointestinal surgery; (2) combined symptoms of heart failure; (3) cardiogenic shock; (4) previous coronary revascularization procedures (e.g., thrombolysis and PCI); (5) combined symptoms with autoimmune diseases; (6) other endocrine diseases such as thyroid; (7) serious damage to organs such as liver and kidney; (8) oral and intravenous antibiotics administration for nearly 1 week, and adjustment of intestinal flora preparation and gastric mucosal protective agent for nearly 1 week; (9) hypertension, obesity, diabetes, and dyslipidemia; (10) pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GOS; | — |
Countries
China
Contacts
Public ContactJiang Tiechao
China-Japan Union Hospital of Jilin University
Outcome results
None listed