breast cancer
Conditions
Interventions
Group P:general anesthesia + pectoral nerve block II
Group E:general anesthesia + erector spinae plane block
Sponsors
First Affiliated Hospital of He'nan University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: American society of anesthesiologists (ASA) physical status I to II, aged > 18 years, elective women who underwent modified radical mastectomy for unilateral breast cancer.
Exclusion criteria
Exclusion criteria: Regional blockade contraindications (infection, local anesthesia allergy, coagulopathy, use of anticoagulant drugs); history of mental illness and chronic pain; neuropathy in the chest; alcohol or opioid abusers; severe cardiopulmonary dysfunction; The liver or kidney is obviously abnormal; BMI > 30 kg/m2, the participants are rejected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative sufentanil dosage;Whether rescue analgesic is needed 24 hours after surgery (NRS = 4);total postoperative morphine consumption in the first 24 h; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative (T0) HR, MBP, HR, MBP at the beginning of the operation (T1), 5 min (T2), 30 min (T3), 60 min (T4), and end (T5); and T1, T2 Difference between HR and MBP;NRS scores at 3, 6, 12, and 24 h after rest and activity (cough);The postoperative recovery quality questionnaire (QoR-40) was used to assess the quality of life before and 24h after surgery.;Postoperative nausea, vomiting, dizziness, pruritus;Operation time, patient satisfaction; | — |
Countries
China
Contacts
Public ContactHong Daoxian
First Affiliated Hospital of He'nan University
Outcome results
None listed