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Assessment of safety and efficacy on tourniquet pressure based on LOP in primary total knee arthroplasty

Assessment of safety and efficacy on tourniquet pressure based on LOP in primary total knee arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900020840
Enrollment
Unknown
Registered
2019-01-20
Start date
2019-02-01
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical treatment for degenerative joint disease

Interventions

LOP group:Pneumatic pressure of tourniquet was set based on patient's LOP
Control group:The pneumatic pressure of the tourniquet was set as 250-300mmhg according to the experience

Sponsors

Changzheng Hospital Affiliated to Naval Military University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1) unilateral knee osteoarthritis: according to the guidelines for the diagnosis and treatment of osteoarthritis (Chinese bone science society, 2007 edition), the diagnostic criteria for knee osteoarthritis (ICD-10 M17.901); 2) normal range of preoperative hemoglobin (Hb), normal coagulation function and renal function; 3) color doppler ultrasound of deep veins in both lower limbs was normal; 4) normal limb muscle strength and limb sensation; 5) primary total knee arthroplasty.

Exclusion criteria

Exclusion criteria: 1) anemia; 2) abnormal coagulation function; 3) angina pectoris, history of myocardial infarction, liver and kidney dysfunction; 4) previous neuromuscular disease; 5) mental illness cannot cooperate with functional exercise and follow up; 6) inflammatory arthropathy; 7) revision surgery of knee joint; 8) those who have done physical training or fitness exercises for more than 1h within one week before enrollment.

Design outcomes

Primary

MeasureTime frame
Mb;CPK, creatine phosphokinase;CRP;LDH;IL-1;IL-6;Hb;Degree of thigh swelling;VAS Score;SOD;Muscle strength of femoris quadriceps;Surgical time;Range of motion of the knee joint;

Countries

China

Contacts

Public ContactQirong Qian

Changzheng Hospital Affiliated to Naval Military University

qrqian@126.com+86 17895185569

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026