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Manual lymphatic drainage combined with repetitive transcranial magnetic stimulation for post-stroke type I complex regional pain syndrome: a randomized controlled trial

Manual lymphatic drainage combined with repetitive transcranial magnetic stimulation for post-stroke type I complex regional pain syndrome: an exploratory clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020835
Enrollment
Unknown
Registered
2019-01-20
Start date
2019-02-01
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complex regional pain syndrome

Interventions

experimental group:routine rehabilitation+MLD+rTMS
control group:routine rehabilitation

Sponsors

north branch of Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 40 to 80 years, male or female; 2. According to the "Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke in China" (2014 edition), diagnosed as cerebral infarction; diagnosed as cerebral hemorrhage according to "Guidelines for the diagnosis and treatment of Chinese cerebral hemorrhage" (2014 edition); 3. Comply with the CRPS diagnostic criteria proposed by the IASP (Budapest standard); 4. CRPS classification is type I (without peripheral nerve injury); 5. CRPS progress period: within 6 months; 6. The vital signs are stable, without serious speech and cognitive impairments, which can be easily communicated and can be combined with rehabilitation therapy; 7. Voluntary signing of informed consent and willingness to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Peripheral nerve injury or disease history; 2. History of external injuries, fractures, and muscle tendon injuries in the affected limbs; 3. Limb thrombosis on the affected side; 4. History of rheumatic diseases; 5. Serious infections such as erysipelas; 6. Severe cardiovascular, respiratory, liver and kidney diseases, unstable clinical symptoms; 7. History of tumor disease; 8. Severe malnutrition; 9. There are contraindications for MLD and rTMS; 10. Participating in other relevant clinical researchers at the same time; 11. Pregnant.

Design outcomes

Primary

MeasureTime frame
Hand volume;Degree of pain;motor function;mental status;

Countries

China

Contacts

Public ContactBai Yulong, Qiu Xiao

Huashan Hospital, Fudan University

dr_baiyl@fudan.edu.cn+86 13816853959

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026