hemifacial spasm
Conditions
Interventions
Group A:the test drug is 5ug/kg butorphanol
Group B:the test drug is 10ug/kg butorphanol
Group C:the test drug is 20ug/kg butorphanol
Group D:the test drug is normal saline
Sponsors
Liaoning People's Hospital
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Primary hemifacial spasm; 2. Patients with no surgical contraindication who are scheduled to undergo microvascular decompression of the facial nerve under general anesthesia; 3. Aged 25-60 years, body mess index 18-30, ASA I or II.
Exclusion criteria
Exclusion criteria: 1. Poor patient compliance 2. Recurrence of primary hemifacial spasm after operation 3. Pregnant or lactating woman 4. A person with a well-defined diagnosis of a severe mental disorder, such as schizophrenia, manic-depressive disorder, etc. 5. Previous history of head trauma; 6. Allergy to butorphanol and its components; 7. Patients with a history of alcoholism and drug abuse; 8. Severe hepatic insufficiency or renal insufficiency before randomization; 9. Previous severe hypertension patients; 10. Patients with previous history of cerebral infarction and myocardial infarction.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| the recovery time; | — |
Primary
| Measure | Time frame |
|---|---|
| heart rate, HR;Systolic Blood Pressure, SBP;Diastolic Blood Pressure, DBP;mean arterial blood pressure, MABP;the scores of pain;the scores of postoperative agitation;the scores of ramsay;Bispectral Idex; | — |
Countries
China
Contacts
Public ContactWang Changming
Liaoning people's Hospital
Outcome results
None listed