non-acute infectious wound
Conditions
Interventions
non-PRP treatment group:Targeted antibiotic treatment, wound debridement surgery, wound vacuum suction, wound dressing and Chinese medicine treatment
Autologous PRP treatment group:On the basis of traditional treatment, the application of autologous PRP treatment
Chitosan propolis PRP composite treatment group:Based on traditional treatment, chitosan propolis PRP composite treatment
Sponsors
Gansu Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 90 Years
Inclusion criteria
Inclusion criteria: 1. Inpatients were post-traumatic infections with a course of more than 1 month; 2. wound cultures were positive for bacterial culture, negative for blood culture, and indicators of inflammation (white blood cell count, erythrocyte sedimentation rate, hypersensitive C-reactive protein and procalcitonin) were examined and reviewed; 3. cases related to the previous study showed that the healing time of chitosan propolis PRP composite for chronic soft tissue infection wounds was (36.1±2.50)d, patients can be discharged after treatment of infection and primary and secondary diseases. Each time the material is changed and the dressing change is carried out in the outpatient dressing room; 4. inform the patient that the whole process of the test treatment, the patients who are willing to receive the test treatment are included in the treatment, and the chitosan propolis PRP composite material in the test is accepted. Preparation and use are free, and the rest of the hospitalization costs are self-sufficient.
Exclusion criteria
Exclusion criteria: Patients with tumor, abnormal platelet function, severe anemia, psychosis, blood disease, fibrin synthesis disorder, severe cardiopulmonary insufficiency, severe liver and kidney dysfunction, taking immunosuppressive agents, acute infection, osteomyelitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WBC;ESR;hsCRP;PCT;A/G;pathogen composition;Type of antibiotic use;Antibiotic use time;Hospital stay;Total hospitalization expenses;Wound healing time;Wound clinical recovery rate; | — |
Countries
China
Contacts
Public ContactXING Tao
Gansu Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed