artrial fibrillation
Conditions
Interventions
A:Super Wide Left Atrial Circumferential Ablation
B:Routine Pulmonary Vein Antrum Isolation
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18 to 80 years; 2) Subjects with persistent AF documented by ECG recording and history; 3) Be refractory or intolerant to antiarrhythmic drug, or refuse to use antiarrhythmic medications.
Exclusion criteria
Exclusion criteria: 1) Moderate to severe valvular disease; 2) Congenital heart disease; 3) History of previous catheter ablation for AF; 4) Left atrial size = 60mm; 5) Left ventricular ejection fraction < 40%; 6) Significant pulmonary dysfunction; 7) Thrombus in the left atrium despite anticoagulation in therapeutic range; 8) Contraindication to anticoagulation ; 9) History of thoracotomy or cardiac surgery; 10) Subjects that are pregnant; 11) Life expectancy less than 12 months; 12) Unable to provide informed written consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint will be recurrence of any ECG documented atrial tachyarrhythmias (>30 seconds) after a single procedure without anti-arrhythmic drugs (AADs) between 3 and 12 months post intervention. ; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of severe intra-and postoperative complications, procedure duration, fluoroscopy time, recurrence of different types of atrial tachyarrhythmias; | — |
Countries
China
Contacts
Public ContactBing Han
Xuzhou Central Hospital
Outcome results
None listed