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Non-surgical treatment is possible to treat left ventricular free wall rupture post acute myocardial infarction

Non-surgical treatment is possible to treat left ventricular free wall rupture post acute myocardial infarction

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900020757
Enrollment
Unknown
Registered
2019-01-17
Start date
2019-01-10
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AMI

Interventions

Case series:Nil

Sponsors

Tianjin Chest Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: AMI is diagnosed according to at least two of the following three criteria: ischemic chest pain or chest tightness lasting for more than 30 min; Sublinguinal administration of nitroglycerin showed no remission, and ST segment elevation of two consecutive leads (I,II,III, aVL, aVF leads =1.0mm or chest leads V1~V6= 2.0mm), and myocardial enzyme level increased by more than 2 times. The diagnostic criteria for LVFWR were progressive exacerbation of heart failure or sudden electromechanical separation, slow ventricular rate, acute jugular venous dilation, and cyanosis of the head and neck.Patients without electro-mechanical separation had acute non-arrhythmic hypotension (systolic blood pressure =80mm Hg). Ultrasound showed a rapid increase in newly developed pericardial effusion or pericardial effusion in the original pericardial effusion with or without cardiac tamponade, and doppler examination confirmed the presence of ventricular wall insufficiency with flow signals passing through the free wall. Subacute LVFWR depends on pericardial effusion with or without pseudoaneurysm and mild or severe cardiac tamponade. Doppler examination confirmed the presence of incomplete ventricular free wall structure and transmural blood flow signals. According to ultrasonic changes, it can be divided into two types: outflow type and oozing type.

Exclusion criteria

Exclusion criteria: No

Design outcomes

Primary

MeasureTime frame
30-day survival;pseudoaneurysm;LVEF;Thickness of pericardial effusion;Crevasse diameter;Pericardial effusion drainage rate;Invasive ventilation lasts for days;IABP lasts for days;

Secondary

MeasureTime frame
C-reactive protein;NT-proBNP;CK-MB;TNI;Cr;

Countries

China

Contacts

Public ContactMingdong Gao

Tianjin Chest Hospital

gaomd000@sinia.com+86 15320083229

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026