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Determination of the 50% effective concentration of methoxamine when given as fixed-rate infusion to prevent of hypotension during spinal anesthesia: an up-down sequential allocation study

Determination of the 50% effective concentration of methoxamine when given as fixed-rate infusion to prevent of hypotension during spinal anesthesia: an up-down sequential allocation study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900020741
Enrollment
Unknown
Registered
2019-01-16
Start date
2019-01-14
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after spinal anesthesia

Interventions

methoxamine group:infusion of methoxamine

Sponsors

West China Second University Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Pregnant women with a singleton pregnancy between 37 to 42 weeks of gestation, age greater than 20 yr, ASA class I- II, weighting less than 100kg, height between 150 and 180 cm undergoing elective cesarean delivery under spinal-epidural anesthesia were enrolled in this study

Exclusion criteria

Exclusion criteria: Those with placental accreta, placenta previa, morbid obesity, hypertensive disease of pregnancy, diabetes, cardiac disease and who failed in the spinal anesthesia placement were excluded.

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure;—

Secondary

MeasureTime frame
Apgar scores;umbilical arterial blood gas analysis;Maternal complications;—

Countries

China

Contacts

Public ContactZhou Jieshu

West China Second University Hospital

270541587@qq.com+86 15008285449

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026