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The analgesic effect of ultrasound-guided dexmedetomidine combined with ropivacaine superficial anterior serratus block on thoracoscopic lobectomy and the effects of inflammatory response, stress response and chronic pain

The analgesic effect of ultrasound-guided dexmedetomidine combined with ropivacaine superficial anterior serratus block on thoracoscopic lobectomy and the effects of inflammatory response, stress response and chronic pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020734
Enrollment
Unknown
Registered
2019-01-15
Start date
2019-01-15
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracoscopic lobectomy

Interventions

A:0.375% ropivacaine 30ml superficial anterior serratus block
B:0.375% ropivacaine 30ml was mixed with dexmedetomidine 1ug/kg for superficial anterior serratus block
C:blank control

Sponsors

The first affiliated hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing selective thoracoscopic lobectomy in the department of thoracic surgery of our hospital from January 2019 to August 2019 2. Male and female aged 18 to 75 years old; 3. ASA I-III; 4. Normal cognitive function; 5. Subjects will participate in the study voluntarily and have signed the informed consent

Exclusion criteria

Exclusion criteria: 1. A history of chronic pain syndrome before surgery; 2. A prior history of mental or psychiatric illness; 3. Previous history of chest surgery; 4. Infection at the puncture site; 5. Communication difficulties; 6. Alcohol or drug abuse; 7. Evidence of serious cardiovascular, kidney, blood or liver disease; 8. Subjects refuse to participate in this study; 9. other analgesics were used within 1 week before inclusion.

Design outcomes

Primary

MeasureTime frame
Visual analogue rating;Quality of life assessment scale;Opioid dosages;he number of times and the first pressing time of the analgesic pump;Additional analgesia in the ward;

Countries

China

Contacts

Public ContactGu Erwei

Department of anesthesiology, the first affiliated hospital of Anhui Medical University

ay_guew_mz@163.com+86 13966663478

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026