malignant biliary strictures
Conditions
Interventions
Group RFA:intraductal radiofrequency ablation+biliary stent placement
Group I125:intraductal Iodine-125 seed + biliary stent placement
Sponsors
the First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Preoperative clinical diagnosis of unresectable primary malignant biliary obstructive jaundice patients 2) Aged 18-90 years old; 3) Clear consciousness and cooperation; 4) An Eastern Cooperative Oncology Group (ECOG) performance status score of 0–3; 5) Expected survival more than 3 months.
Exclusion criteria
Exclusion criteria: 1) Patients with benign biliary obstruction; 2) Patients with resectable tumor; 3) ECOG performance status of 4; 4) Patients with any other preoperative anti-cancer therapy; 5) Patients with Immunosuppressive therapy within 30 days; 6) Placement of bile duct stent or bile duct drainage previously; 7) Patients with metastases; 8) Merging other malignant tumor; 9) Severe mental illness, severe heart, lungs and kidneys disease, etc; 10) Malignant obstructive jaundice by metastatic tumors; 11) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| survival time;complication rate of operation;success rate of operation;patency time of stent; liver function recovery efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| operation time;postoperative hospital stay;total length of stay in hospital; | — |
Countries
China
Contacts
Public ContactRui Liao
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed