Postoperative analgesia
Conditions
Interventions
group O:oxycodone combined with flurbiprofen ester
Group M:Morphine compound flurbiprofen ester
Sponsors
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) selective transforaminal lumbar interbody fusion; 2) Postoperative patient-controlled intravenous analgesia; 3) aged 40-75 years old; 4) BMI <28kg/m2; 5) ASA I or II; 6) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe impairment of Heart, Lung, brain, liver and Kidney function; 2. Intracranial hypertension, severe hypertension (grade III and above) and systolic blood pressure (SBP) > 180mmhg or diastolic blood pressure (DBP) > 110mmhg were not decreased twice in a row; 3. Gastrointestinal bleeding or peptic ulcer; 4. Aspirin asthma or previous history; 5. Allergy to the drugs used in this subject; 6. Long-term preoperative administration of opiates, sedative and analgesic drugs, psychoactive drugs; 7. Taking Elofloxacin, Lomefloxacin, Norfloxacin; 8. Suffering from mental, neuromuscular diseases; 9. Unable to express will correctly, unable to give verbal guidance and cooperation; 10. Hypothyroidism / cortical insufficiency; 11. Prostatic hypertrophy, dysuria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;cumulative dosage of analgesic pump;Effective pressing / total pressing;Remedial analgesic dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of bowel sounds;Abdominal distension rate;Postoperative first exhaust time;Other side effects;Postoperative recovery (first turn over, walk time); | — |
Countries
China
Contacts
Public ContactBin Ji
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Outcome results
None listed