premature ventricular contraction (Qi-Yin deficiency syndrome)
Conditions
Interventions
Group 1:Yangxin Dingji Jiaonang
Group 2:Yangxin Dingji Jiaonang Simulator
Sponsors
Beijing Chao-Yang Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.signing the informed consent voluntarily; 2.Aged 18 to 75 years old; 3.Diagnosis of Qi-Yin deficiency syndrome in accordance with TCM 'palpitation' syndrome; 4.According to the diagnosis of premature ventricular contraction in western medicine and the following indicators: 3000 beats/24 hours = premature ventricular beats = 20000 beats/24 hours; 5.Left ventricular ejection fraction (=50%); 6.Stop using other anti-arrhythmic drugs except beta-blocker (excluding sotalol) for more than 5 half-lives (over 2 weeks of traditional Chinese medicine) before admission.
Exclusion criteria
Exclusion criteria: 1.Those who need to be treated with other antiarrhythmic drugs or means; 2.Grade III atrioventricular block; 3.Complicated with severe organic heart disease (cardiomyopathy, hereditary disease, acute viral myocarditis, rheumatic heart disease); 4.Hyperthyroidism; 5.Digitalis poisoning and electrolyte disturbance; 6.Those who have suffered from acute myocardial infarction in the past year and have undergone PCI or cardiac bypass surgery; 7.Systolic blood pressure (= 160 or =90 mmHg) and/or diastolic blood pressure (= 110 mmHg); 8.Severe history of liver and kidney diseases, such as cirrhosis, chronic active hepatitis and chronic renal insufficiency; 9.Severe gastrointestinal disease that affects drug absorption, distribution, metabolism, and excretion or has undergone gastrointestinal surgery that affects drug absorption (e.g., gastrostomy or intestinal resection) 10.Patients with acute stroke within 6 months; 11.history of malignant tumors, alcohol or drug abuse; 12.women of childbearing age who breast-feeding, pregnancy, planned pregnancy or did not take reliable contraceptive measures; 13.disabled patients who could not cooperate with clinical trials (blindness, deafness, dumbness,dysgnosia retardation, limb disability); 14.Allergy or allergic asthma to the ingredients, excipients and materials used in the test 15.Those who participated in other clinical trials within 3 months before the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total effective rate of ventricular premature beats at week 8; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total effective rate of ventricular premature beats at week 4;Changes in the number of premature ventricular beats at week 4 and 8;Changes of single symptoms of traditional Chinese medicine in 4 and 8 weeks (disappearance rate);Therapeutic effect of atrial premature beats at week 4 and 8; | — |
Countries
China
Contacts
Public ContactYang Xinchun
Beijing Chao-Yang Hospital, Capital Medical University
Outcome results
None listed