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Effect of low-dose dexmedetomidine continuous infusion at the night before surgery on the quality of postoperative recovery

Effect of low-dose dexmedetomidine continuous infusion at the night before surgery on the quality of postoperative recovery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020712
Enrollment
Unknown
Registered
2019-01-14
Start date
2019-01-10
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recovery after surgery

Interventions

Group S:low-dose saline continuous infusion
Group L:low-dose dexmedetomidine continuous infusion
Group M:medium-dose dexmedetomidine continuous infusion
Group H:high-dose dexmedetomidine continuous infusion

Sponsors

Fujian Provincial Hospital the south branch
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) Phase I or II patients for elective surgery, aged 18 to 65 years.

Exclusion criteria

Exclusion criteria: Patients who are allergic to the study drugs, obese patients with a body mass index (BMI) of more than 28, patients with underlying obstructive sleep apnea, patients with a history of chronic pain, or patients who regularly use analgesics.

Design outcomes

Primary

MeasureTime frame
baseline serum ß100;postoperative serum ß100;baseline serum IL-1;postoperative serum IL-1;baseline anxiety score;postoperative anxiety score;—

Secondary

MeasureTime frame
Intraoperative analgesic dosage;postoperative analgesic dosage;Postoperative complications;Postoperative hospitalization date;—

Countries

China

Contacts

Public ContactWu Xiaodan

Fujian Provincial Hospital the South Branch

wxiaodan@sina.com+86 13055291720

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026