Migraine
Conditions
Interventions
low-dose group:Oral 4.5g sucrose / day + Vitamin C (100mg / day) + conventional treatment
medium-dose group:Oral 9.0g sucrose / day + Vitamin C (100mg / day) + conventional treatment
medium-dose group 2:Oral 8.0g brown sugar / day + Vitamin C (100mg / day) + conventional treatment
controlled group:Oral Vitamin C (100mg / day) + conventional treatment
Sponsors
School of Public Health, Harbin Medical University, Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male or female, 18-65 years old and signed the consent; 2. Diagnosed as migraine without aura and migraine with aura (Migraine with typical aura Retinal migraine) according to the diagnostic criteria specified by the International Classification of Headache Disorder, 3rd edition (ß version ); 3. Migraine present for at least one years and patients having 2-14 attacks per month; 4. Moderate to severe pain (VAS=3.6) which affected the work and learning.
Exclusion criteria
Exclusion criteria: 1. Having analgesics more than 10 times due to the migraine attacks every month; 2. Special types of migraine such as ophthalmoplegiahemiplegic migraine type; 3. Cluster headache, tension-type headache and other secondary headache disorders; 4. Combined with diabetes mellitus and hepaticrenal hematopoietic system and other serous primary diseases; 5. Having severe mental disease or allergies; 6. Pprophylactic drugs of migraine such as ß-blockerscalcium channel blockersantiepileptic drugs and so on were taken in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the duration of migraine attack;change in the frequency of migraine attack;Headache days(days with more than 4h of headache irrespective of pain quality and associated symptoms);Migraine days (days with typical features of migraine);Headache accompanied symptoms;Visual Analogue Scale score;Blood sugar;Glycosylated hemoglobin (HbA1C); | — |
Secondary
| Measure | Time frame |
|---|---|
| The frequency of analgesics;Life quality of migrainers;Headache impact test;Adverse effects; | — |
Countries
China
Contacts
Public ContactYashuang Zhao
School of Public Health, Harbin Medical University, Harbin Medical University
Outcome results
None listed