malignant biliary strictures
Conditions
Interventions
Group 1:ERCP-guided intraductal radiofrequency ablation
Group 2:percutaneous transhepatic intraductal radiofrequency ablation
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Preoperative clinical diagnosis of unresectable primary malignant biliary obstructive jaundice patients 2) Aged 18-90 years old; 3) clear consciousness and cooperation; 4) an Eastern Cooperative Oncology Group (ECOG) performance status score of 0–3; 5) expected survival more than 3 months.
Exclusion criteria
Exclusion criteria: 1) patients with benign biliary obstruction; 2) patients with resectable tumor; 3) ECOG performance status of 4; 4) patients with any other preoperative anti-cancer therapy; 5) patients with Immunosuppressive therapy within 30 days; 6) placement of bile duct stent or bile duct drainage previously; 7) patients with metastases; 8) merging other malignant tumor; 9) severe mental illness, severe heart, lungs and kidneys disease, etc; 10) malignant obstructive jaundice by metastatic tumors; 11) pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival time;complication rate of RFA;success rate of RFA;patency time of stent;liver function recovery efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| operation time;postoperative hospital stay;total length of stay in hospital; | — |
Countries
China
Contacts
Public ContactRui Liao
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed