osteoporsis and osteopenia
Conditions
Interventions
Group A:Gushukang capsule 4 grain/per time twice a day
Group B:femostone (2/10)
Group C:Gushukang capsule + femostone (Gushukang capsule 4 grain/per time twice a day, and femostone (2/10) 1 grain per day)
Sponsors
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) According to the recommendations of the International Society for Clinical Bone Density (ISCD) in 2007 and the American Academy of Radiology (ACR) in 2013, the patients who have osteoporosis or osteopenia; (2) Perimenopausal women or women who have been menopausal for more than one year; (3) women aged 40-60 years; (4) Climacteric-related symptoms (FSH=25IU/L).
Exclusion criteria
Exclusion criteria: 1. Complicated with chronic nephritis, uremia, hyperthyroidism, hyperparathyroidism, chronic gastroenteritis, liver disease, diabetes mellitus, rheumatoid arthritis and Cushing syndrome can cause secondary osteoporosis; 2. Ovariectomy; 3. Those who have used hormones, calcitonin or other drugs that affect bone metabolism in the past three months; 4. Patients with severe cardiovascular and cerebrovascular diseases or liver and kidney failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lumbar QCT;0?,12?,24?;PINP/CTX/25-hydroxyvitamin D; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood biochemistry;Blood lipid;Mammary gland molybdenum target/mammary gland B-mode ultrasonography;Blood Routine;electrocardiogram;B-mode ultrasonography of vagina;Blood Routine;Blood lipid;Blood biochemistry;PINP/CTX/25-hydroxyvitamin D; | — |
Countries
China
Contacts
Public ContactXiangyan Ruan
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Outcome results
None listed