retinopathy of prematurity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Observation group: children with severe ROP requiring treatment; Control group: The premature who with infants gestational age ? 34w or premature birth weight <2000g and without ROP in the same neonatal intensive care unit (NICU) of observation group have the matched gestational age, birth weight and correct gestational age(birth weight difference is less than 200 g, birth gestational age difference less than 2 weeks, correct gestational age difference less than 2 weeks).
Exclusion criteria
Exclusion criteria: 1. Parents request to withdrew from the study or infants who have not completed ROP screening; 2. Congenital malformation genetic metabolic disease exists in preterm infants; 3. Severe complications (such as sepsis, necrotizing enterocolitis, neonatal respiratory distress syndrome, severe metabolic disorder, morbidity of the control group, etc.) or death occurred during the study; 4. The mother of the study subject has a history of serious diseases and medication during pregnancy; 5. The control group develop ROP in subsequent follow-up examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| biomarkers of blood of retinopathy of prematurity (ROP); | — |
Contacts
Shenzhen eye hospital