Chronic hepatitis B
Conditions
Interventions
Case series:No intervention
Sponsors
302 Hospital of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
1 Years to 16 Years
Inclusion criteria
Inclusion criteria: 1. The diagnostic criteria for chronic hepatitis B and the indications for IFN treatment in children are in line with the European 2013 ESPGHAN Guidelines for the Diagnosis and Treatment of Chronic Hepatitis B in Children; 2. patients who are about to accept or are undergoing IFN a1b; 3. 1 year old = age = 16 years old, male or female; 4. From the 3 months before the application of interferon therapy, no other antiviral drugs have been treated; 5. Agree to sign the Informed Consent Form (Children aged 1-6 years may be signed by the guardian; children between the ages of 7 and 11 are in principle signed by the child and the guardian; those over the age of 12 must be signed by the child and the guardian).
Exclusion criteria
Exclusion criteria: 1. Combined with HCV, HDV or HIV-infected persons; 2. Receiving other medical treatments that may affect the pharmacokinetics or pharmacodynamics of IFN; 3. Those who have major diseases such as serious heart or brain diseases; 4. Combined with mental abnormalities, such as dementia; 5. Merged with mentally ill persons; 6. The research doctor considered it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IFN a1b serum drug concentration; | — |
Countries
China
Contacts
Public ContactJingfeng Bi
302 Hospital of the Chinese People's Liberation Army
Outcome results
None listed