Connective Tissue Disease
Conditions
Interventions
Gold Standard:Multi-modality cardiac imaging
markers 
of 
and 
to 
investigate 
predictors 
RVH
Sponsors
Department Of Cardiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Inclusion Criteria for CTD with RVH: (1) Aged 18-80 years old; (2) Definite connective tissue diseases diagnosis; (3) Echocardiography demonstration (later confirmed by CMR) of a hypertrophic RV when maximal end-diastole RV wall thickness >4 mm due to CTD. 2.Inclusion Criteria for CTD without RVH: (1) Aged 18-80 years old; (2) Definite connective tissue diseases diagnosis; (3) Echocardiography demonstration (later confirmed by CMR) that maximal end-diastole RV wall thickness =4 mm. 3.Inclusion Criteria for Control group: (1) Absence of known systemic diseases; (2) Normal examinations; (3) Aged 18-80 years old; (4) Providing written informed consent.
Exclusion criteria
Exclusion criteria: 1. Documented coronary artery disease or prior angiography for coronary artery disease (>50% stenosis); 2. Patients with known congenital heart disease or other systemic diseases that might induce RVH; 3. Patients with standard metallic contraindications to CMR or an estimated glomerular filtration rate < 30 ml/min/1.73 m^2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ECV;native T1;SPE, SEN, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactPu Jun
Department of Cardiology, Renji Hospital, School of Medicine, Shanghai Jiaotong Universityo
Outcome results
None listed