Dynamics gut microbiome in the development of gestational diabetes mellitus

Conditions

Gestational diabetes mellitus

Zixin Zhong, Rongjing An, Shujuan Ma, Na Zhang, Xian Zhang et al. (11 authors)

Biology2024-07-283 citations

Study on the relationship between DNA methylation of target CpG sites in peripheral blood and gestational diabetes during early pregnancy.

Wang X, Huang J, Zheng Y, Long S, Lin H, Zhang N, Tian M, Wu X, An R, Ma S, Tan H.

2021-10-148 citations

10.1038/s41598-021-99836-2

Alterations in Gut Microbiota of Gestational Diabetes Patients During the First Trimester of Pregnancy

Shujuan Ma, Yiping You, Lingting Huang, Sisi Long, Jiayue Zhang et al. (10 authors)

Frontiers in Cellular and Infection Microbiology2020-02-27131 citations

10.3389/fcimb.2020.00058

Interventions

Gestational diabetes mellitus group:None

Control group:None

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. singleton pregnancy and natural conception; 2. 10-13+6 week; 3. splanned to complete regular obstetric examinations and the final delivery at current hospital.

Exclusion criteria

Exclusion criteria: 1. with diseases that might affect microbiome composition or glucose metabolism, like pre-pregnancy diabetes, thyroid disorders, hypertension, inflammatory bowel disease and cardiovascular diseases; 2. had received any antibiotic treatment throughout the current pregnancy; 3. had acute infection within 2 weeks before sample collection.

Design outcomes

Primary

Measure	Time frame
16S rRNA of gut microbiome;Metagenome of gut microbiome;Serum metabolism spectrum;	—

Countries

China

Contacts

Public ContactTan Hongzhuan

Central South University

tanhz99@qq.com+86 086-731-88858435

Outcome results

None listed