premenstrual syndrome
Conditions
Interventions
PMS group (2Hz):tVNS intervention
PMS group (25Hz):tVNS intervention
HC group (2Hz):tVNS intervention
HC group (25Hz):tVNS intervention
PMS treatment group:tVNS treatment according to course of treatment
PMS control group:False tVNS therapy
PMS waiting group:No intervention
Sponsors
The First Affiliated Hospital of Guangxi University of traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria of this study were as follows: referring to the PMS standard recommended by the American Society of Obstetricians and Gynecologists (American College of Obstetricians and Gynecologists, ACOG) in 2000. (1) according to PMS diagnostic criteria; (2) regular menstrual cycle (28 ±3 days); (3) aged between 18 and 45 years; (4) no combination of drugs or other clinical related treatments during the trial; (5) Right handedness.
Exclusion criteria
Exclusion criteria: (1) patients with other mental disorders or drugs, alcohol dependence; (2) somatic diseases, severe head trauma, severe infection or surgery in the near future; (3) lactating or pregnant women; (4) patients with irregular menstrual cycle; (5) to participate in other clinical drug observation researchers; (6) to have no response to tVNS; (7) to have contraindication with tVNS; (8) to have a history of smoking. Other causes of cirrhosis (e.g. drug, alcohol, hepatitis C virus, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain function BOLD data;Brain 3D-T1WI data;Brain DTI data;Brain MRS data;Brain ASL data; | — |
Countries
China
Contacts
Public ContactDemao Deng
The First Affiliated Hospital of Guangxi University of traditional Chinese Medicine
Outcome results
None listed