Crohn Disease
Conditions
Interventions
Case series:exclusive enteral nutrition
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) radiologic, endoscopic, and histologic diagnosis of CD according to ESPEN guidelines(9); (2) CD patients required a laparoscopic approach for bowel resection; (3) the score of Nutritional Risk Screening (NRS-2002) was more than 2; (4) for the EEN group, patients had EEN therapy for at least 4 weeks before surgery by nasogastric tube, and the daily calorie intake was 25-30 kcal/kg of body weight; (5) for the non-EEN group, patients received a liquid diet, semiliquid diet, oral enteral nutrition, or intravenous solution to improve their nutrition status and maintain their water-electrolyte balance; (6) patients received other preoperative optimization, such as quitting smoking, and stopping corticosteroid treatment before surgery. Patients with incomplete laboratory data, poor compliance with EEN therapy, or multivisceral resection were excluded. In our hospital, CD patients were always encouraged to receive nutrition treatment before surgery, but whether or not patients accepted a nasogastric tube were their decisions.
Exclusion criteria
Exclusion criteria: The exclusive enteral nutrition used in this study before the surgery was Peptison liquid (Nutricia, Amsterdam, Netherlands), which was composed of vitamins, minerals, hydrolyzed whey protein peptide, trace elements, very little fat, vegetable oil, and maltodextrin(16). The content of major nutrients included carbohydrates (17.6 grams), lipids (1.7 grams), and protein (4 grams) per 100 mL of liquid. The calorie density was 1 kcal/mL with an osmolarity of 440 mosm/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative complications; | — |
Countries
China
Contacts
Public ContactZhou Wei
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed