gastric cancer
Conditions
Interventions
single-dose group:Patients in the single-dose group received a “single-dose oral carbohydrate” regimen: 500 mL of oral 10% glucose solution 2-3 h before surgery
dual-dose group:patients in the dual-dose group received 'dual-dose oral carbohydrates' regimen: 1000ml of 10% oral glucose solution 10 hours before surgery and 500 mL of oral 10% glucose solution 2-3
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) patients diagnosed with gastric cancer by gastroscopy biopsy and who are scheduled for gastrectomy; (2) aged 18-80 years old; (3) If the patient has undergone radiotherapy or chemotherapy before surgery, the time between the last radiotherapy or chemotherapy and the surgery is >= 1 month; (4) non-emergency surgery; (5) No gastric emptying disorder factors; (6) not taking drugs that affect metabolism, blood sugar or insulin levels and gastric emptying; (7) informed consent of patients and their families.
Exclusion criteria
Exclusion criteria: (1) combined with severe brain, heart, lung, liver and kidney diseases; (2) patients with diabetes; (3) distant metastasis, recurrent tumors and multiple primary cancers; (4) blood transfusion within 2 weeks before surgery, nutritional support treatment; (5) morbid obesity [body mass index (BMI) > 40]; (6) patients with metabolic syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin resistance index;Comfort;Intraoperative aspiration; | — |
Secondary
| Measure | Time frame |
|---|---|
| CD3+, CD4+, CD8+, CD4+/CD8+;Tumor necrosis factor-a, Interleukin (IL)-6, C reactive protein;Postoperative rehabilitation effect;Postoperative complication rate; | — |
Countries
China
Contacts
Public ContactLi Ka
West China Hospital, Sichuan University
Outcome results
None listed