Effect of Xuebijing injection on macrophage polarization in patients with peritonitis-induced sepsis

Effect of Xuebijing injection on macrophage polarization in patients with peritonitis-inducede sepsis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900020593

Enrollment

Unknown

Registered

2019-01-09

Start date

2019-01-20

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peritonitis-induced sepsis

Interventions

Experiment group:Xuebijing plus routine therapy

Control group:Routine therapy

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Sepsis-3 criteria from Society of Critical Care Medicine (SCCM) /European Society of Intensive Care Medicine (ESICM); 2. Aged 18 to 65 years; 3. Diagnosed as acute peritonitis; 4. Obtain informed consent.

Exclusion criteria

Exclusion criteria: 1. Diagnosis of sepsis for more than 48 h; 2. Pregnant and lactating women; 3. Severe primary disease including unrespectable tumours, blood diseases and Human Immunodeficiency Virus (HIV); 4. Severe liver and kidney dysfunction (single liver or kidney SOFA score = 3 points); 5. Use of an immunosuppressant or having an organ transplant within the previous 6 months; 6. Participating in other clinical trials in the previous 30 days.

Design outcomes

Primary

Measure	Time frame
28-day mortality;APACHE II score;	—

Secondary

Measure	Time frame
proinflammatory cytokines;Anti-inflammatory factors;DAO;IFABP;D-lactate;	—

Countries

China

Contacts

Public ContactQuan Zhao

the First People's Hospital of Yunnan Province

13759579998@163.com+86 13759579998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026