gingivitis
Conditions
Interventions
Test Group:toothpastes containing 2% Zinc Citrate
Control:use the matching placebo toothpaste without Zinc Citrite
Sponsors
West China Stomatological Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
25 Years to 34 Years
Inclusion criteria
Inclusion criteria: 1) Subjects had to possess at least 20 uncrowned permanent natural teeth, in good general health without significant systemic diseases; 2) Subjects aged 18 and 65 years; 3) Pregnant or breast feeding women were excluded from the study; 4) Subjects were required to present at baseline with PLI (Quiley&Hein)= 2, GI (Loe-Silness) = 1, BI= 1, Periodontal pocket depth=5mm; 5) Subjects who signed an informed consent form and completed clinical trials as required.
Exclusion criteria
Exclusion criteria: 1) Subjects who had allergic histories to ingredients of the test toothpastes; 2) With severe tartar; 3) Subjects who were currently taking drugs that could affect the test results; 4) Subjects who had taken antibiotics within one month before participating in the study; 5) Subjects who had open caries or lesions in the mucous membranes inside the oral cavity; 6) Subjects suffering from severe periodontitis; 7) Individual who participated in any other similar clinical study or panel test will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival Index;Bleeding index;Plaque Index;Real time PCR; | — |
Countries
China
Contacts
Public ContactBiao Ren
West China Stomatological Hospital of Sichuan University
Outcome results
None listed