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A study for the improved effect of Chinese Herb Basil on EGFR-TKI and platinum in Non-small Cell Lung Cancer Patients by Temperature-Controlled NanoVelcro CTC purification systems

A study for the improved effect of Chinese Herb Basil on EGFR-TKI and platinum in Non-small Cell Lung Cancer Patients by Temperature-Controlled NanoVelcro CTC purification systems

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020589
Enrollment
Unknown
Registered
2019-01-09
Start date
2019-01-10
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Group 1:Gefinitib/Erlotinib
Group 2:Gefinitib/Erlotinib & Basil
Group 3:standard chemotherapy
Group 4:standard chemotherapy & basil

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Diagnosed with non-same cell lung cancer by pathology; 2. TCM syndrome differentiation is qi deficiency and phlegm dampness syndrome; 3. Aged between 18-80 years old; 4. ECOG Performance Status 0-3; 5. Local lesions and/or distant metastatic lesions can be measured or evaluated; 6. Normal function of bone marrow, liver, kidney, heart and lung; 7. Estimated survival time more than 3 months; 8. Can understand the study well and sign the written informed consent.

Exclusion criteria

Exclusion criteria: 1. pregnant woman; 2. Patients with uncontrolled brain metastases; 3. Combine with other tumors; 4. Patients with mental disorders; 5. Combine with active tuberculosis and other serious infectious diseases; 6. Elimination criteria: (1) During the course of the experiment, if the patient requests to withdraw from the study, the reason for the withdrawal should be recorded as much as possible, and other treatment plans that are willing to accept should be taken; (2) If there is drug allergy or unanticipated serious adverse reactions during the treatment, and it may be related to the experimental drug, the treatment should be stopped in time and other treatment should be carried out.

Design outcomes

Primary

MeasureTime frame
abundance of EGFR mutation;

Secondary

MeasureTime frame
BRCA1 and ERCC1 mRNA level;blood biochemical indexes;Response Rate;

Countries

China

Contacts

Public ContactFeng Bing

Guangdong Provincial Hospital of Chinese Medicine

bing19831@163.com+86 15013099083

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026