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Clinical observation for single intravenous pre-injection of small dose of remifentanil to inhibit cough caused by sufentanil during induction of general anesthesia

Clinical observation for single intravenous pre-injection of small dose of remifentanil to inhibit cough caused by sufentanil during induction of general anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020587
Enrollment
Unknown
Registered
2019-01-09
Start date
2019-01-01
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough caused by sufentanil during general anesthesia induction

Interventions

C group:No remifentanil given
R group:Intravenous injection of remifentanil 0.3ug/kg before induction

Sponsors

The First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18~65 years old; 2. BMI: 18~28kg/m2; 3. ASA I~II grade; 4. Patients undergoing elective general anesthesia surgery.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or lactation women; 2. With a history of drug allergy; 3. Cognitive or mental illness; 4. Severe cardiovascular and cerebrovascular diseases, liver, kidney and hematopoietic diseases; 5. Long-term use of analgesics or hormones, drug abuse History; 6. Those who participated in other clinical trials or researchers considered inappropriate to participate in this experiment.

Design outcomes

Primary

MeasureTime frame
Coughing times;—

Secondary

MeasureTime frame
Mean arterial pressure;Heart rate;—

Countries

China

Contacts

Public ContactJiehao Sun

The First Affiliated Hospital of Wenzhou Medical University

linwendong2000@163.com+86 13819705490

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 20, 2026