chronic nonhealing wound
Conditions
Interventions
Group 1:auto-lipoconcentrate combined with split thickness skin graft
Group 2:split thickness skin graft
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 81 Years
Inclusion criteria
Inclusion criteria: (1) patients signed the informed consent on the day of the age of 18 or above; (2) a diagnosis of chronic nonhealing wound; (3) ulcer for 2 weeks or more; (4) wound area 3 cm2 or higher; (5) humerus ankle index is between 0.7 to 1.2; (6) stable vital signs, regular examination showed that can tolerate operation; (7) patients' mental state is good who can follow the doctor's advice and visit regularly; (8) understanding and willing to participate in the clinical trials of this item and provide the signed informed consent.
Exclusion criteria
Exclusion criteria: (1) the existing disease affects wound healing (e.g., malignant tumor, autoimmune disease); (2) patients in immunosuppression in screening period because of the underlying disease, long-term immunosuppressive therapy or the use of high doses of corticosteroids (i.e. accept or 40 mg daily prednisone or prednisone amount, for 2 weeks or higher) in screening period; (3) it is difficult to control the high blood sugar (HbA1c > 12.0%); (4) with severe uncontrolled disease or acute systemic infections and merging other serious heart, lung disease, severe encephalopathy and other organs; (5) patients with mental illness; (6) researchers think that should not be included in person; (7) The pregnant women, fertile women without appropriate precautions ,breastfeeding women in the screening period or planing for pregnancy in a month after the end of the study; (8) Being patient to participate in the study at any time in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin survial rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| healing rate;healing quality; | — |
Countries
China
Contacts
Public ContactZhang Jian
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed