liver fibrosis/cirrhosis
Conditions
Interventions
Gold Standard:Pathological examination: The METAVIR score system was applied for differentiating liver fibrosis. Inflammatory activity was graded as follows: A0=none, A1=mild, A2=moderate and A3=sever
Sponsors
Shangdong Provincial Hospital Affiliated to Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged at least 18 years old; (2) presence of hepatitis B surface antigen; (3) histologic staging of liver fibrosis from surgery operation.
Exclusion criteria
Exclusion criteria: (1) co-infection with HCV, HIV or other chronic liver disease; (2) regular consumption of 20g or more alcohol weekly; (3) previous liver surgery or liver transplantation; (4) inadequate adjacent liver tissue away from lesions for more than 2cm; (5) elastography failure; (6) portal or hepatic veins embolus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver stiffness;Stage of liver fibrosis;Microvascular density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serological index; | — |
Countries
China
Contacts
Public ContactQiang Zhu
Shangdong Provincial Hospital Affiliated to Shandong University
Outcome results
None listed