Skip to content

A study for the value of PetCO2, S100B in the treatment of abdominal cardiopulmonary cerebral resuscitation and its prognostic evaluation

A study for the value of PetCO2, S100B in the treatment of abdominal cardiopulmonary cerebral resuscitation and its prognostic evaluation

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020558
Enrollment
Unknown
Registered
2019-01-08
Start date
2019-01-01
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac arrest

Interventions

Group 1:chest compression CPR
Group 2:abdominal compression-decompression CPR

Sponsors

Sisen Zhang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Comply with the indications for abdominal compression-decompression CPR, no contraindications; Indications: general anesthesia patients with chest traumatic cardiac respiratory arrest, respiratory muscle weakness and respiratory depression, especially those with Chest compression contraindications such as chest deformity and trauma, rib fracture and blood and pneumothorax. Contraindications: abdominal trauma, diaphragmatic rupture, abdominal organ bleeding, abdominal aortic aneurysm, abdominal giant masses; (2) adults weighing 40-150kg, regardless of gender; (3) the patient's close relatives agreed to use the abdominal compressive CPR device to treat the patient and signed the informed consent. The rescue of cardiac arrest needs to race against time and time is urgent. In order not to delay the rescue time of patients, all patients first obtain oral consent from their relatives before the test, and then sign the relevant detailed informed consent documents.

Exclusion criteria

Exclusion criteria: (1) no indication for abdominal lift CPR; (2) contraindication of abdominal compressive CPR or abdominal organ injury during abdominal compressive CPR;Contraindications: abdominal trauma, diaphragmatic rupture, abdominal organ bleeding, abdominal aortic aneurysm, abdominal giant masses; (3) the patient's close relatives do not agree to use abdominal compressive cardiopulmonary resuscitation device for treatment; (4) cardiac arrest time was too long (CA time>10 min), without signs of resuscitation; (5) weight less than 40Kg or more than 150Kg; (6) patients with previous severe respiratory diseases (such as emphysema, extensive bronchiectasis, pulmonary interstitial fibrosis, etc.) and neurological diseases (including cro-ya disease, alzheimer's disease, amyotrophic lateral sclerosis and recent stroke, etc.); (7) patients with cardiac valvular disease, aortic dissection and other effects on hemodynamic stability.

Design outcomes

Primary

MeasureTime frame
ROSC rate;

Secondary

MeasureTime frame
partial pressure of end-tidal carbon dioxide;Hemodynamic data;Blood gas analysis results;Types and incidence of complications;Rate of ROSC and mortality rate 7 days after ROSC;Contents of neuron specific enolase(NSE);S100B protein;Content of glial fibrous acidic protein (GFAP);brain natriuretic peptide (BNP);

Countries

China

Contacts

Public ContactSisen Zhang

Southern Medical University Affiliated Zhengzhou People’s Hospital

2362176700@qq.com+86 13937120886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026