gastric cancer patinents
Conditions
Interventions
Group 1:methoxamine
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Signed the informed consent form, voluntarily participated in this study, and did not participate in other clinical trials at the same time; 2. Aged at least 65 years old; 3. Anesthesiologists physical status class I or II,BMI<40 kg/m2; 4. Elective subtotal gastrectomy (endoscopic or laparotomy)
Exclusion criteria
Exclusion criteria: 1. Emergency surgery; 2. ASA grade III or above; 3. Severe hepatic and renal insufficiency, history of hyperthyroidism, pheochromocytoma; 4. Serious cardiovascular and cerebrovascular disease, hemodynamic instability; 5. Chronic obstructive pulmonary disease requires bronchodilators in patients, pulmonary hypertension; 6. Mean arterial pressure can seriously affect blood loss (controlled hypotension is required intraoperatively); 7. Take nonsteroidal anti-inflammatory drugs for nearly a month, and recently use tricyclic antidepressants or monoamine oxidase inhibitors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cerebral oxygen saturation;The incidence of AKI; | — |
Secondary
| Measure | Time frame |
|---|---|
| perfusion index;The incidence of intraoperative adverse events;Intraoperative fluid usage;first aerofluxus time;Postoperative compliance;Postoperative hospital stay;Cystatin-C;30-day all-cause mortality;length of hospitalization; | — |
Countries
China
Contacts
Public ContactQi Dunyi
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed