The influence and prevention of malnutrition caused by oxidative stress induces intestinal flora imbalance in patients of chronic obstructive pulmonary disease.

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900020522

Enrollment

Unknown

Registered

2019-01-06

Start date

2018-12-31

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary diseases

Interventions

Experience group:inhalation of hydrogen

control group:inhalation of oxygen

Eligibility

Sex/Gender

All

Age

20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis of COPD is confirmed by the subject's symptoms, signs, and pulmonary function tests, in line with the guidelines for the diagnosis and treatment of COPD developed by the Chinese Medical Association Respiratory Diseases Association in 2013; 2. Age and gender are not limited; 3. FEV1/FVC <70% and FEV1 <80% of the predictive value after inhalation of bronchodilator.

Exclusion criteria

Exclusion criteria: (1) Obesity, BMI = 28; (2) Hyperlipidemia (plasma total cholesterol > 5.17 mmol /l or triglycerides > 2.3 mmol/l); (3) Diagnosed diabetic patients; (4) Diagnosed hypertension patients; (5) Alzheimer's disease patients; (6) Diagnosis of tumor patients; (7) Anyone who has used any antibiotic in the past 2 weeks; (8) Patients who are unfit for this study considered by the investigators.

Design outcomes

Primary

Measure	Time frame
Bacteria spectrum;Nutrition metabolism;	—

Countries

China

Contacts

Public ContactZeguang Zheng

First Affiliated Hospital of Guangzhou Medical University

13503034012@139.com+86 13503034012

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026