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Effect of Granulocyte Colony Stimulating Factor (G-CSF) on Endometrium after Traumatic Intrauterine Adhesion Dissection

Effect of Granulocyte Colony Stimulating Factor (G-CSF) on Endometrium after Traumatic Intrauterine Adhesion Dissection

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900020506
Enrollment
Unknown
Registered
2019-01-03
Start date
2018-05-01
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrauterine adhesions

Interventions

Study group after severe intrauterine adhesions separation:Granulocyte colony-stimulating factor Intrauterine perfusion and oral artificial cycle
Control group after severe intrauterine adhesions separation:Oral artificial cycle
Study group after moderate intrauterine adhesions separation:Granulocyte colony-stimulating factor Intrauterine perfusion and oral artificial cycle
Control group after moderate intrauterine adhesions separation:Oral artificial cycle

Sponsors

West China Second Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) intrauterine adhesions following surgery for various conditions diagnosed by hysteroscopy; 2) aged 20 to 40 years old; 3) transvaginal ultrasound detection the thickness of the double inner membrane is less than 7mm in endometrial middle luteal phase Period before hysteroscopic surgery; 4) there are fertility requirements.

Exclusion criteria

Exclusion criteria: 1) combined reproductive system malformations; 2) combined with other diseases of the reproductive system, such as uterine fibroids, adenomyosis, etc.; 3) severe internal surgical diseases with pregnancy contraindications; 4) combined with Artificial cycle treatment contraindications; 5) history of tuberculosis in the reproductive system.

Design outcomes

Primary

MeasureTime frame
Degree of intrauteruine adhesion;endometrial thickness;Menstrual volume;pregnance;

Secondary

MeasureTime frame
Endometrial blood flow signal;

Countries

China

Contacts

Public ContactLiangzhi Xu

West China Second Hospital, Sichuan University

liangzhixv@sina.com+86 18180609131

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026