Polycystic ovary syndrome
Conditions
Interventions
OCP group:Oral contraception
Control group:None
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20-40 years PCOS patient; 2. Fallopian tubes, at least unilateral is patency indicated by HSG or laparoscopy; 3. Husband's sperm analysis: sperm concentration >= 15 million sperm per milliliter; motility >= 40%; progressive motility >= 32%; 5. Consent to ovulation induction by letrozole; 6. Hyperandrogenism, clinical, Ferriman-Gallwey Score >=5; biochemical, Total T = 50 ng/dL, a free or weakly bound T = 10 ng/dL or a FAI = 5.
Exclusion criteria
Exclusion criteria: 1. Hyperprolactinaemia, Atypical congenital adrenal hyperplasia, Cushing's syndrome, Androgen-secreting tumors, Acromegaly, diabetes mellitus; 2. Women with cardiac, respiratory or kidney disease who are not able to pregnancy; 3. Women who are suspicious or determined to be pregnant; 4. Women who breastfeed within 6 months; 5 Women who are the use of hormone drugs or other medications (including herb medicine) within 3 months, these drugs may interfere intervention effects; 6. Women with contraindications using oral contraceptives, such as history of breast cancer, history of venous thrombosis, history of migraines, severe liver history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rate;Ovulation rate;Clinical pregnancy rate;Pregnancy loss rate;Total testosterone;Sex hormone binding globulin; | — |
Countries
China
Contacts
Public ContactTang HuiRu
Peking University Shenzhen Hospital
Outcome results
None listed