coronary heart disease
Conditions
Interventions
group1: conventional therapy combine with Qing-xin -Jie-yu Decoction
group2:conventional therapy combine with placebo
Sponsors
Xiyuan Hospital Affiliated to the China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Those with a definite history of MI, or coronary stenosis (> 50%) confirmed by coronary angiography or spiral CT, or stable condition (> 1 month) after treatment of acute coronary syndrome (ACS) (PCI or drug intervention); 2. Aged 18 to 75 years; 3. High sensitivity C-reactive protein was found between 3 and 10 mg/L; 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. having a history of AMI, UA Underwent PCI or CABG less than one months; 2. Having Other heart diseases, Severe cardiopulmonary dysfunction; 3. bad-controlled hypertension (systolic blood pressure >=160mmHg and diastolic blood pressure >=100mmHg); 4. Having Acute cerebrovascular disease; 5. Having other serious primary diseases of hepatic, renal and hematopoietic system, or psychosis; 6. malignancy arrhythmia (such as paroxysmal ventricular tachycardia) are relapsing repeatedly recently; 7. Woman in Pregnancy, Planned pregnancy or lactation period; 8. Underwent craniocerebral, thoracic and abdominal operation in the past four weeks and having bleeding tendency; 9. participated in other clinical trials in the past a month; 10. allergic constitution or a known allergy to the study medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| high-sensitivity c-reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| sCD40L;MMP-9;IL-6;TNF-a;sVCAM-1;SDS;angina pectoris grade;BSS score;Electrocardiogram;hyperlipidemia;Seattle angina questionnaire;TCM syndrome;MCP-1; | — |
Contacts
Public ContactXu Hao
Xiyuan Hospital Affiliated to the China Academy of Chinese Medical Sciences
Outcome results
None listed