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Therapeutic effect of high frequency repetitive transcranial magnetic stimulation with different frequencies on patients with post-stroke depression

Therapeutic effect of high frequency repetitive transcranial magnetic stimulation with different frequencies on patients with post-stroke depression

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800020468
Enrollment
Unknown
Registered
2018-12-31
Start date
2019-01-01
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke depression

Interventions

Group 1:5Hz transcranial magnetic stimulation + antidepressant + conventional treatment
Group 2:5Hz transcranial magnetic stimulation + antidepressant + conventional treatment
Control group:False stimulation+ antidepressant + conventional treatment

Sponsors

The Affiliated Hospital of Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis of the disease is in line with the guidelines for the diagnosis and treatment of acute cerebral ischemic stroke in China in 2014 and the guidelines for the diagnosis and treatment of cerebral hemorrhage in China; 2. Transcranial computed tomography (CT) and/or magnetic resonance imaging (MRI) confirmed stroke; 3. The diagnosis of depressive episodes meets chinese classification and diagnostic criteria of mental disorders-3(CCMD-3) or the diagnostic and statistical manual of mental disorders ?(DSM-VI) for depressive episodes; 4. Hamilton depression rating scale =8 points; 5. Signing informed consent.

Exclusion criteria

Exclusion criteria: 1. Mentally diseases patients before stroke; 2. Patients with severe disturbances of consciousness, aphasia, understanding of expression disorders and cognitive impairment (MMSE=9 points); 3. The patient has a history of seizures; 4. Intracranial, cardiac, etc. have implanted metal objects.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale;

Secondary

MeasureTime frame
remission rate;ADL;MBI;Cortical latency;response rate;

Countries

China

Contacts

Public ContactHu Jiali

The Affiliated Hospital of Qingdao University

787048329@qq.com+86 18974861781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026