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The Effect of Female Genital Tract Microecology on Persistent HPV Infection and Its Immune Mechanisms

The Effect of Female Genital Tract Microecology on Persistent HPV Infection and Its Immune Mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800020453
Enrollment
Unknown
Registered
2018-12-30
Start date
2019-01-02
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer

Interventions

Reproductive group:none
Post-menopausal group:none

Sponsors

Guangzhou Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Reproductive and post-menopausal women (25-65 of age); 2. Chinese Nationality; 3. Understand the purpose of this study, willing to participate, and sign the patient informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnancy; 2. HPV vaccinated; 3. Current acute vaginal infection; 4. On antibiotics, antifungals or antivirals currently or within the previous three months; 5. On hormonal therapy currently or within the previous three months; 6. HIV positive and Hepatitis; 7. Immunodeficiencies and autoimmune disorders; 8. Using probiotics and prebiotics; 9. Type I or Type II diabetes.

Design outcomes

Primary

MeasureTime frame
Cervicovaginal microbial diversity;Immune cytokines;Estrogen level;HPV status (Positive or negative);Oral microbial diversity;Immune cell population;—

Countries

China

Contacts

Public ContactQingli Shen

Guangzhou Women and Children's Medical Center

qingli.shen@yahoo.com+86 18102706499

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026