FindTrial
Sign In

The Value of High-throughput Sequencing in the Diagnosis of Infectious Diseases of the Central Nervous System

The Value of High-throughput Sequencing in the Diagnosis of Infectious Diseases of the Central Nervous System

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800020442
Enrollment
Unknown
Registered
2018-12-29
Start date
2018-10-01
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious Diseases of the Central Nervous System

Interventions

Gold Standard:Clinical performance + laboratory examination + routine etiological examination
Index test:High-throughput&#32
Sequencing

Sponsors

Neurology Department of Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 14 to 80 years old; 2. Informed consent are retrieved from the patient; 3. Patients with highly suspected infectious diseases of the CNS, including: tubercular meningitis, CNS viral infections, purulent meningitis, cryptococcal meningitis and non-infectious CNS disease (inflammatory demyelinating disease, meningeal carcinomatosis and connective tissue disease associated encephalopathy).

Exclusion criteria

Exclusion criteria: 1. Patients who refuse lumbar puncture; 2. Patients who cannot perform lumbar puncture because of lumbar deformity; 3. Patients with parafunction of blood coagulability; 4. Patients at risk of cerebral hernia.

Design outcomes

Primary

MeasureTime frame
causative agent;—

Countries

China

Contacts

Public ContactJia-Tang Zhang

Neurology Department of Chinese PLA General Hospital

zjt1128@aliyun.com+86 10-55499121

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 18, 2026