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To evaluate the changes of IL-17 phenotype before and after intervention of Compound Caoshi silkworm granule in stable stage of chronic obstructive pulmonary disease

To evaluate the changes of IL-17 phenotype before and after intervention of Compound Caoshi silkworm granule in stable stage of chronic obstructive pulmonary disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800020441
Enrollment
Unknown
Registered
2018-12-29
Start date
2019-01-15
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

Six symptoms groups:Based on the compound Caoshi Silkworm Granule, plus different Chinese medicines

Sponsors

Jinhua Municipal Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Choose outpatient, community and discharged patients aged 40-80 years, including Smokers and non-smokers; 2. COPD of stage II-III was clinically diagnosed. The predicted value of FEV1 ranges from 30% to 70% after bronchodilator administration. 3. There were at least two times of acute exacerbation in the first two years of admission. 4. Clinical stability was observed within 2 weeks before admission. 5. Provide written informed consent and be able to fulfill research requirements

Exclusion criteria

Exclusion criteria: 1. Patients with bronchial asthma, cystic fibrosis, active pulmonary tuberculosis, pneumonia, Bronchopneumonia, bronchiectasis, lung cancer, lung metastases and other progressive fatal diseases, 2. Severe cardiovascular disease, severe neurological disease and severe liver function damage or kidney impairment; 3. Patients with poor compliance.

Design outcomes

Primary

MeasureTime frame
IL-17;

Countries

China

Contacts

Public ContactChen Hui

Jinhua Municipal Central Hospital

jhzxyych@sina.com+86 13566785191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026