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Correlation between RNF213 polymorphism and Postoperative Collateral Formation in Patients With Moyamoya Disease

Correlation between RNF213 polymorphism and Postoperative Collateral Formation in Patients With Moyamoya Disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800020439
Enrollment
Unknown
Registered
2018-12-29
Start date
2019-01-02
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moyamoya disease

Interventions

Case series:Nil

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) written informed consent had been obtained; 2) more than 8 years old and less than 60 years old; 3) cerebral digital subtraction contrast angiography (DSA) revealed severe stenosis or occlusion of the distal internal carotid or proximal middle and anterior cerebral arteries with prominent lenticulostriate 'moyamoya collaterals'; 4) received surgical revascularization; 5) having undergone preoperative and postoperative cerebral digital subtraction angiography or magnetic resonance angiography.

Exclusion criteria

Exclusion criteria: patients with coagulation dysfunction.

Design outcomes

Primary

MeasureTime frame
Matsushima scale;Zhao level;

Secondary

MeasureTime frame
preoperative collateral formation;New clinical vascular events (ischemic stroke/ hemorrhagic stroke/ TIA);Modified Rankin Scale score changes (continuous) and dichotomized at percentage with score 0-2 vs. 3-6 at 6 month follow-up;Collateral Grade;

Countries

China

Contacts

Public ContactQian Zhang

Beijing Tiantan Hospital, Capital Medical University

zhangqianchina@yahoo.com+86 13611075005

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026