Peripheral precocious puberty
Conditions
Interventions
treatment group:transcutaneous electrical acupoint stimulation combined with auricular acupoints and health education
control group:health education
Sponsors
Beijing Municipal Administration of Hospitals
Eligibility
Sex/Gender
Female
Age
3 Years to 8 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of peripheral precocious puberty; (2) Girls before the age of 8 have secondary sexual characteristics such as breast development and pubic hair premature appearance; (3) In gonadotropin releasing hormone (GnRH) stimulation test, the peak value of LH was less than 3.3-5.0 IU/L and the peak value of LH/FSH was less than 0.6; (4) Parents agree and sign informed consent; (5) Previous treatment without any medication or intervention
Exclusion criteria
Exclusion criteria: (1) Central precocious puberty; (2) heterosexual precocious puberty in girls; (3) precocious puberty caused by gonadal tumors and adrenal diseases; (4) suspicious chromosomal abnormalities or hereditary diseases with special appearance, skin abnormalities, growth and development abnormalities; (5) It does not meet the inclusion criteria and can not adhere to the treatment course; (6) Participants in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum sex hormones;breast Tanner stage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gynecological pelvic ultrasonography;TCM symptoms;BMI; | — |
Countries
China
Contacts
Public ContactLiu Lili
Beijing Jishuitan Hospital
Outcome results
None listed