The effect of early plasmapheresis on the organ function in the hypertriglyceridemic pancreatitis: a multicenter randomized controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800020415

Enrollment

Unknown

Registered

2018-12-28

Start date

2019-02-01

Completion date

Unknown

Last updated

2021-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Acute Pancreatitis

Interventions

without PE:without PE in early time

PE:PE in early timr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2. a clear diagnosis of AP; within 48h after upset; 3. serum TG > 11.3mmol/L,and meet one or more item of the following: Lactic acid > 2 mmol/L and pH 38.5 degrees C or 90 beats/min; Respiration > 20 times per minute or PaCO 2 > 32 mmHg; WBC count >12 000/ml or 10%; 4. Organ failure (modified Marshall score).

Exclusion criteria

Exclusion criteria: 1. AP during pregnancy; 2. Pancreatic cancer, AP caused by chronic pancreatitis; 3. May die in the next 48h, or give up treatment; 4. Chronic obstructive pulmonary disease, coronary heart disease, chronic kidney disease, hematologic diseases, malignant tumors, systemic autoimmune diseases, or long-term oral glucocorticoid; 5. For a variety of non-medical reasons to give up treatment.

Design outcomes

Primary

Measure	Time frame
mortality;organ function;clinical outcome;	—

Secondary

Measure	Time frame
inflammation;TG;FFA;	—

Countries

China

Contacts

Public ContactTong Zhihui

Jinling Hospital affiliated to Nanjing University

njzyantol@hotmail.com+86 13851948781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026