Tuberculosis
Conditions
Interventions
Gold Standard:Clinical outcome
protein 
S100A9, 
ORM2, 
IL1F6 
and 
SOD1 
Sponsors
Beijing Chest Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: The patients were diagnosed with TB according to combined clinical criteria from the World Health Organization. Included patients with pulmonary TB had a positive sputum smear or culture result. Patients with pulmonary TB were further stratified according to disease severity, into a severe pulmonary TB (STB) group and a mild pulmonary TB (MTB) group. Patients were considered to be STB if three or more lung lobe alterations were observed in a chest computed tomography (CT) scan, with respiratory failure or hypoxemia
Exclusion criteria
Exclusion criteria: (1) Aged < 18 years old; (2) Patients with malignant tumors; (3) Immune system diseases or those receiving immunotherapy; (4) HIV, hepatitis B and hepatitis C virus infection; (5) Complications during pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SPE, SEN, ACC, AUC of ROC;plasma protein S100A9, ORM2, IL1F6 and SOD1 levels; | — |
Countries
China
Contacts
Public ContactLIUQIUYUE
Beijing Chest Hospital, Capital Medical University
Outcome results
None listed