nasopharyngeal carcinoma
Conditions
Interventions
Sponsors
Department of Radiology, Sun Yat-Sen University Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients between 18-65 years old; 2. ECOG score 0-1; 3. Patients with newly histologically confirmed nasopharyngeal carcinoma without any history of anti-tumor therapy or other malignancies; 4. With normal bone marrow, liver and renal function 14 days before enrollment as followed: 1) HGB = 9g/dL; 2) ANC > 1.5*10^9/L, PLT > 100*10^9/L , TBIL< 1.5xULN; ALT and AST < 2×ULN; PT/APTT < 1.5×ULN; Creatinine clearance < 1.5xULN; 5. Patients must offer signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients have received anti-tumor therapy, including chemotherapy, radiotherapy and surgery; 2. Patients have been or suspicious to be allergic to MR contrast or metal; 3. Patients have MR contraindications, including those individuals with pacemaker implantation, magnetic materials in the body or other situations that could not get close to the high-intensity magnetic field; 4. Patients have experienced claustrophobia; 5. In pregnant or lactating Female; 6. Patients could not cooperate with follow-up because of the following reasons, such as psycology, society, family or geography; 7. With severe uncontrolled infections (>grade 2, NCI-CTC v.4.0); 8. Patients with history of heart disease: congestive heart-failure > NYHA grade 2, active coronary heart disease (patients suffered from myocardial infarction 6 months before enrollment could be accepted), arrhythmia that needs anti-arrhythmia therapy (beta receptor blocker and digoxin could be accepted) or uncontrolled hypertension; 9. Patients have diseases that might influence the drug administration, distribution, metabolization or excretion; 10. Patients have the history of other malignancies; 11. Patients without signing informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosis quality of the overall images; | — |
Secondary
| Measure | Time frame |
|---|---|
| Readability evaluation;incidence rate of the artifact;Odds Ratio;hazard ratio;area under curve; | — |
Countries
China
Contacts
Public ContactChuanmiao Xie
Sun Yat-Sen University Cancer Center
Outcome results
None listed