hepatic cirrhosis and portal hypertension
Conditions
Interventions
Group 1:Laparoscopic splenectomy plus endoscopic variceal ligation
Group 2:pericardial devascularization
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged from 18 - 70 years old male and female; (2) Clinical diagnosis of cirrhotic with portal hypertension patients with esophageal variceal hemorrhage (3) Severe esophageal varices with or without severe varices of gastric fundus veins were confirmed by endoscopy. (4) Child-Pugh Score less than 9; (5) Peripheral blood platelets < 50 *10^9/L; (6) Volunteered to join the research.
Exclusion criteria
Exclusion criteria: (1) History of malignant tumors; (2) HIV-positive ; (3) History of immunodeficiency or autoimmune diseases; (4) Organ dysfunction; (5) History of mental disorders; (6) History of drug abuse; (7) Participated in other clinical trials; (8) With serious cardiopulmonary or other underlying diseases; (9) Other unsuitable situation; (10) Patients are reluctant to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The disappearance rate of severe esophageal varices; | — |
Secondary
| Measure | Time frame |
|---|---|
| rate of rebleeding;The perioperative complication rate; | — |
Countries
China
Contacts
Public ContactLiu Bo
The Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed