chronic liver and chronic kidney diseases
Conditions
Interventions
Gold Standard:Clinical outcomes include chronic liver disease: ALT, AST, ALP, GGT, TC/CT, MR or ultrasound report in one month
chronic kidney diseases: GFR, Cr.
Index test:3T MR functional sequences: fat quantitative sequence (fat fraction), DWI sequence (diffusion indexes, kurtosis and perfusion fraction, et al), susceptibility sequence (susceptibility, phas
Sponsors
Shuguang Hospital affiliated with Shanghai University of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Chronic liver and kidney diseases patients, including non-alcoholic fatty liver disease (mild, moderate-severe), hepatocirrhosis (Child-Pugh ABC) and chronic kidney disease 1 to 5; age from 18 to 70; Stable vital signs; informed consents for participating in the study should be obtained from patients themselves or at least one legal guardian and assents should be obtained; participants fully realize the exam process and matters needing attention.
Exclusion criteria
Exclusion criteria: Unable to cooperate and move during the MR scanning; have any issues affecting MRI scanning and imaging quality, such as heart pacemakers, metal implants, retractors or claustrophobia; psychiatric and psychological disease; tumor or serious diseases such as cardiovascular disease; pregnant woman.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fat fraction;diffusion indexes;susceptibility;renal blood flow;kurtosis;perfusion fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| T1 values;R2* values;T2 values;phase; | — |
Countries
China
Contacts
Public ContactZhan Songhua
Shuguang Hospital affiliated with Shanghai University of TCM
Outcome results
None listed